Brewers vs. Pirates Prediction: Best Bet with Keller vs. Priester Today?

by | May 24, 2025 | mlb

Mitch Keller Starting Pitcher Pirates

The Milwaukee Brewers (25-27) continue their weekend series against the Pittsburgh Pirates (18-34) at PNC Park on Saturday afternoon. After Friday night’s dramatic 6-5 extra-inning loss, the Brewers look to bounce back with Quinn Priester facing his former organization. Meanwhile, Pittsburgh starter Mitch Keller desperately needs a win, sitting at a disappointing 1-6 despite solid underlying numbers. This matchup features two NL Central rivals heading in opposite directions, with Milwaukee trying to climb back to .500 while Pittsburgh continues to struggle.

Quick Picks:
Best Bet: Pirates ML (-114) ★★★★☆
Top Prop: Mitch Keller Over 5.5 Strikeouts (-115) ★★★☆☆
Value Play: Under 8.5 Runs (-110) ★★★☆☆

Milwaukee Brewers vs Pittsburgh Pirates Betting Odds & Latest Line Movement

Market Milwaukee Brewers Pittsburgh Pirates
Moneyline -105 -114
Run Line +1.5 (-190) -1.5 (+160)
Total Over 8.5 (-110) Under 8.5 (-110)

Opening Line: Pirates -110, Total 8.5

Sharp Money Analysis: Where Pro Bettors Are Placing Their Wagers

Early sharp money has pushed the Pirates from -110 to -114 despite their poor overall record. Professional bettors are recognizing the value in backing Keller at home against his former teammate Priester, who has struggled with control issues. The total has remained steady at 8.5 with balanced action on both sides, though there’s been some under money coming in over the past 12 hours.

Pitching Matchup: Quinn Priester vs Mitch Keller – Who Has the Edge?

Milwaukee Brewers: Quinn Priester (1-2, 4.66 ERA)

  • 38.2 innings pitched with a concerning 1.47 WHIP
  • Struggling with control: 22 walks to just 25 strikeouts
  • Former Pirates first-round pick traded to Milwaukee this offseason
  • Has allowed at least 3 earned runs in 4 of his last 5 starts

Pittsburgh Pirates: Mitch Keller (1-6, 3.88 ERA)

  • Much better than his record indicates with 58.0 IP and 1.31 WHIP
  • Strong K/BB ratio with 48 strikeouts to 17 walks
  • Receiving just 2.4 runs of support per start
  • 3.12 ERA in his last three starts with 19 strikeouts

Advantage: Pittsburgh

Bullpen Breakdown

Both bullpens were heavily taxed in Friday night’s extra-inning affair. The Brewers’ relief corps has been middle-of-the-pack this season with a 4.11 ERA (14th in MLB), but they’ve thrown the fourth-most innings in baseball. Pittsburgh’s bullpen has struggled overall with a 4.67 ERA (23rd), though they’ve shown improvement lately with a 3.88 ERA over the past two weeks. Ryan Borucki got the win last night despite allowing a run, and Pittsburgh will likely avoid using him today.

Key Betting Trends & Team Statistics That Matter

  • Pirates are 11-6 when they out-hit their opponents
  • Brewers are 19-4 when they out-hit their opponents
  • Milwaukee is just 10-17 on the road this season
  • Pittsburgh is 12-15 at home this season
  • The Brewers are 5-5 in their last 10 games, averaging just 3.7 runs per game
  • The Pirates are 4-6 in their last 10 games with a 3.62 ERA during that stretch
  • Keller is 2-1 with a 3.42 ERA in his career against the Brewers

Player Spotlight: Rhys Hoskins Heating Up For Brewers

Rhys Hoskins has been one of Milwaukee’s hottest hitters, going 13-for-34 (.382) with three doubles and three home runs over his last 10 games. After a slow start to the season, Hoskins has found his power stroke and provides the Brewers with a dangerous middle-of-the-order bat. He’ll be a challenging matchup for Keller, who will need to be careful with his pitch selection against the veteran slugger.

PNC Park Factor: How the Venue Influences Today’s Game

PNC Park has historically played as a pitcher-friendly venue, especially for right-handed power hitters due to the deep left-center gap. With temperatures expected to be in the mid-60s and minimal wind, conditions should be neutral to slightly favorable for pitchers. The park’s spacious outfield could benefit Keller, who induces more ground balls than Priester and has better command. This gives Pittsburgh an additional edge in today’s matchup.

Expert Prediction & Best Bets for Brewers-Pirates Showdown

Primary Play: Pirates ML (-114)

Mitch Keller is due for positive regression with his 1-6 record not reflecting his solid 3.88 ERA and strong peripheral numbers. Meanwhile, Quinn Priester has been inconsistent and walks too many batters (5.1 BB/9), which is a recipe for disaster. Keller knows the Brewers well from his years in the NL Central, and I expect him to outpitch Priester in this matchup. The Pirates should provide enough run support against their former prospect to secure a home win.

Strong Value Play: Under 8.5 Runs (-110)

Despite Priester’s control issues, I see value in the under today. Both offenses have been struggling, with Pittsburgh averaging just 3.02 runs per game (29th in MLB) and Milwaukee at 4.33 (15th). After an emotional extra-inning game last night, fatigue could be a factor for both lineups. Keller has pitched better than his record indicates, and even if Priester gets into trouble, the spacious PNC Park should help limit the damage.

Worth Considering: Oneil Cruz to Hit a Home Run (+400)

After a multi-homer game last night, Cruz is seeing the ball extremely well right now. The lanky shortstop has incredible raw power, as evidenced by his 117.9 mph bomb on Friday night. Priester has already allowed 7 home runs in just 38.2 innings this season, and if he makes a mistake over the plate, Cruz could capitalize for the third time in two days.

Player Props Worth Targeting in Today’s Matchup

Player Prop Odds Rating
Mitch Keller Over 5.5 Strikeouts -115 ★★★★☆
Oneil Cruz To Hit a Home Run +400 ★★★☆☆
Bryan Reynolds Over 1.5 Total Bases +115 ★★★☆☆
Rhys Hoskins Over 0.5 RBIs +160 ★★★☆☆

Final Thoughts: Don’t Be Fooled By Records – Keller Is The Better Pitcher Today

While the Pirates’ overall record is dismal at 18-34, Mitch Keller represents their best chance to win games. His 1-6 record masks what has been solid performance, and the former All-Star is due for better luck. Quinn Priester has talent but continues to struggle with command, walking too many batters and not missing enough bats (5.8 K/9).

The Brewers are the better team overall, but Pittsburgh has momentum after last night’s dramatic win, and Keller gives them a significant edge on the mound today. In what should be a relatively low-scoring affair, I expect the Pirates to prevail at home behind a quality start from their ace.

Score Prediction: Pirates 5, Brewers 3

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