Angels vs. Athletics Prediction: Can L.A. Sweep on May 22?

by | May 22, 2025 | mlb

Tyler Anderson Starting Pitcher Los Angeles Angels

Los Angeles Angels (23-25) vs. Oakland Athletics (22-28)
Sutter Health Park – West Sacramento, CA
Thursday, May 22, 2025 – 3:35 PM EDT

Betting Odds

  • Moneyline: Athletics -153, Angels +128
  • Run Line: Athletics -1.5 (+130), Angels +1.5 (-150)
  • Total: Over/Under 10 runs (-110/-110)

Pitching Matchup

Los Angeles Angels: Tyler Anderson (2-1, 3.04 ERA, 1.09 WHIP, 43 Ks)
Oakland Athletics: Luis Severino (1-4, 4.22 ERA, 1.27 WHIP, 45 Ks)

Recent Form

Angels: 7-3 in last 10, riding a six-game winning streak
Athletics: 1-9 in last 10, mired in an eight-game losing streak

Key Injuries

Angels:
– Mike Trout (knee) – Out, but reported running at 80% this week
– Yusei Kikuchi (ankle) – Day-to-day
– Anthony Rendon (hip) – 60-Day IL

Athletics:
– Jacob Wilson (forearm) – Day-to-day
– Zack Gelof (hand) – 10-Day IL

Team Analysis

The Angels have caught fire, winning six straight games and showcasing serious power in the process. They’ve homered in 11 consecutive games, the longest active streak in MLB, with 15 homers during their current six-game winning streak. Logan O’Hoppe has been particularly impressive, blasting two homers in Wednesday’s 10-5 win, including a mammoth 470-footer that ranks as the second-longest homer in baseball this season.

The Athletics, meanwhile, are in freefall. They’ve dropped eight straight contests and have been outscored by a staggering 62-21 during this stretch. Their home record (8-16) has been especially troubling as they continue to struggle in their temporary home at Sutter Health Park in West Sacramento.

Handicapping the Matchup

This pitching matchup is fascinating despite the odds suggesting Oakland has the edge. Tyler Anderson has quietly been effective for the Angels, maintaining a solid 3.04 ERA and showing excellent command. His ability to mix pitches and keep hitters off balance should play well against an A’s lineup that’s pressing during this losing streak.

Luis Severino hasn’t lived up to expectations in Oakland, going 1-4 with a 4.22 ERA. He’s shown flashes of his former Yankees form, but consistency remains elusive. The oddsmakers are showing respect to Severino’s pedigree by making Oakland the favorite, but I see significant value on the Angels side.

The Angels’ lineup is firing on all cylinders right now. Taylor Ward (13 HRs), Logan O’Hoppe (13 HRs), and Zach Neto (8 HRs) provide substantial power, while Jorge Soler has added consistent production since joining the Angels. The A’s do have talented young hitters like Jacob Wilson (.341 BA) and Nick Kurtz (who homered twice yesterday), but they’ve struggled to string together consistent offensive production.

Best Bet: Angels ML (+128) ★★★★☆

I’m absolutely shocked by this line. The Angels have won six straight games, including the first three of this series, while the A’s have dropped eight consecutive contests. Tyler Anderson has been more consistent than Severino this season, and the Angels’ offense is significantly hotter.

The betting market seems to be overvaluing home-field advantage and perhaps Severino’s name recognition, but the current form of these teams tells a much different story. Getting plus money on the surging Angels against the slumping Athletics is one of the best values on Thursday’s MLB slate.

The Angels have scored at least 6 runs in all three games of this series, while the A’s pitching staff has allowed 38 runs during their current five-game homestand. The Angels’ bats should stay hot against Severino, who’s been vulnerable to the long ball this season.

At +128, the Angels moneyline offers tremendous value, and I’d play it down to +110. The team momentum, recent head-to-head results, and pitching matchup all point toward another Angels victory to complete the four-game sweep.

Additional Value Play: Over 10 Runs (-110) ★★★☆☆

These teams have already combined for 15 runs in yesterday’s contest, and the Angels have been an offensive juggernaut during their winning streak. The A’s have shown some power potential as well, with Nick Kurtz homering twice on Wednesday. Given the hitting-friendly dimensions of Sutter Health Park and the offensive trends in this series, the over offers solid supplemental value.

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