Cubs vs. Reds Prediction & Best Bets | Pitching Duel Brewing in Cincinnati

by | May 24, 2025 | mlb

Andrew Abbott Cincinnati Reds Starting Pitcher

The Chicago Cubs (31-20) look to continue their three-game winning streak as they face the Cincinnati Reds (25-27) at Great American Ball Park on Saturday afternoon. This NL Central matchup features two undefeated starting pitchers who have been dominant this season, setting up what could be a compelling pitcher’s duel despite the hitter-friendly confines.

Quick Picks:
Best Bet: Under 9.5 Runs (-120) ★★★★☆
Top Prop: Colin Rea Over 5.5 Strikeouts (+105) ★★★☆☆
Value Play: Cubs -1.5 (+129) ★★★☆☆

Cubs vs. Reds Betting Odds & Latest Line Movement

Market Cubs Reds
Moneyline -127 +107
Run Line -1.5 (+129) +1.5 (-154)
Total Over 9.5 (+100) Under 9.5 (-120)

Opening Line: Cubs -125, Total 9.5

Sharp Money Analysis: Where Pro Bettors Are Placing Their Wagers

Despite yesterday’s high-scoring affair (Cubs won 13-6), sharp money has been coming in on the under for today’s game. Professional bettors recognize the pitching talent on display and seem to be respecting both Rea and Abbott’s early-season dominance. There’s also been some slight movement toward the Cubs on the moneyline, suggesting sharps like Chicago’s chances to continue their momentum.

Pitching Matchup: Colin Rea vs Andrew Abbott – Who Has the Edge?

Cubs: Colin Rea (3-0, 2.38 ERA)

  • 41.2 IP, 32 Ks, 11 BBs, 1.20 WHIP
  • Has yet to lose a decision this season
  • Averaging just under 7 strikeouts per 9 innings
  • Coming off 6 shutout innings against Miami last week

Reds: Andrew Abbott (3-0, 1.80 ERA)

  • 35.0 IP, 43 Ks, 15 BBs, 1.11 WHIP
  • Striking out batters at an impressive 11.1 K/9 rate
  • Has allowed 2 or fewer runs in all of his starts this season
  • Limited opponents to a .186 batting average

Advantage: Slight edge to Abbott based on dominance and strikeout rate, though both pitchers have been excellent.

Bullpen Breakdown

The Cubs’ bullpen has been middle-of-the-pack with a 3.75 ERA this season, but they did get a boost yesterday with the return of Ryan Brasier from the injured list. Meanwhile, the Reds’ relief corps has been slightly better with a 3.52 ERA, though they were taxed in yesterday’s loss, with four relievers seeing action. Edge goes to the Cubs for having a fresher bullpen heading into today’s game.

Key Betting Trends & Team Statistics That Matter

  • Cubs are 8-2 in their last 10 games, outscoring opponents by 40 runs
  • Reds are 5-5 in their last 10 games with a +2 run differential
  • Cubs are 29-7 when recording 8+ hits this season
  • Reds are 17-5 when scoring 5+ runs this season
  • Cubs are 16-10 on the road this year (61.5%)
  • Reds are 13-13 at home this season
  • The Cubs have scored double-digit runs in 11 of their first 51 games, the most since 1898

Pete Crow-Armstrong: Cubs’ Rising Star

Pete Crow-Armstrong has been on a tear recently, hitting .372 over his last 10 games with 4 home runs. Yesterday, he blasted two home runs, including a grand slam, and drove in 6 RBI in the Cubs’ victory. He’s now tied for third in MLB with 14 home runs and sits fourth with 45 RBI on the season. Abbott will need to be careful with Crow-Armstrong, who’s showing power to all fields.

Great American Ball Park Factor: How the Venue Influences Today’s Game

Great American Ball Park is notorious for being hitter-friendly, particularly for home runs. The ballpark has consistently ranked as one of the most homer-friendly venues in baseball. However, today’s matchup features two pitchers who have excelled at limiting hard contact. The weather forecast calls for temperatures in the low 70s with light winds, which could help keep the ball in the park more than usual for this venue.

Expert Prediction & Best Bets for Cubs-Reds Showdown

Primary Play: Under 9.5 Runs (-120)

This is a classic case where the ballpark reputation has inflated the total. Both Rea and Abbott enter with sub-2.40 ERAs and undefeated records. While the Cubs’ offense has been red-hot lately, Abbott has been nearly unhittable this season. Likewise, Rea has been a revelation for Chicago, consistently working deep into games and limiting damage. Even in a hitter-friendly park, these pitchers should control the action for at least 5-6 innings each.

Strong Value Play: Cubs -1.5 (+129)

Chicago has been dominating opponents lately, with their last 8 wins coming by multiple runs. They’ve outscored opponents by 40 runs over their last 10 games, and their offense is clicking on all cylinders. At +129, there’s value on the Cubs to win by multiple runs, especially with how well they’ve been playing. The Cubs’ lineup could wear down Abbott as the game progresses, opening the door for a late rally against the Reds’ bullpen.

Worth Considering: Colin Rea Over 5.5 Strikeouts (+105)

Rea has averaged just under 7 Ks per 9 innings this season, and the Reds strike out at a high rate (8.90 K/game). Cincinnati’s lineup can be aggressive, which should play into Rea’s hands. If he can work 6 innings as he has been, he should clear this strikeout total.

Player Props Worth Targeting in Today’s Matchup

Player Prop Odds Rating
Pete Crow-Armstrong Over 1.5 Total Bases +115 ★★★★☆
Elly De La Cruz To Record a Stolen Base +160 ★★★☆☆
Andrew Abbott Over 6.5 Strikeouts -115 ★★★★☆
Seiya Suzuki To Hit a Home Run +375 ★★★☆☆

Final Thoughts: Expect a Pitching Showcase

While yesterday’s game turned into a slugfest, today should be completely different with two highly effective starters on the mound. The Cubs have the momentum and a more dynamic offense right now, but Abbott is the type of pitcher who can silence even the hottest bats. I expect a low-scoring affair early with the Cubs eventually breaking through against the Reds’ bullpen in the later innings.

When handicapping today’s game, I can’t ignore how dominant both starting pitchers have been. The total of 9.5 seems inflated based on yesterday’s result and the reputation of Great American Ball Park, but the pitching matchup suggests we’re in for a much lower-scoring affair. I’ll take the Under 9.5 as my best bet, with the Cubs to cover the run line offering strong value.

Score Prediction: Cubs 5, Reds 3

100% Free Play up to $1,000 (Crypto Only)

BONUS CODE: PREDICTEM

BetOnline

MLB Betting Guide

New to betting on baseball? We’ve got you covered! Our comprehensive how to bet on baseball article explains all the different types of wagers offered at the sportsbooks including money lines, over/unders, run lines, parlays and more! Also get tips and strategies to increase your odds of beating the bookies!