Cubs vs Reds Prediction & Best Bets | Rubber Match at Great American Ball Park

by | May 25, 2025 | mlb

Ben Brown Chicago Cubs

The Chicago Cubs and Cincinnati Reds face off in a crucial NL Central rubber match on Sunday afternoon at Great American Ball Park. After splitting the first two games of the series, both teams are looking to claim the series victory and gain momentum as we approach the Memorial Day milestone. The Cubs have been riding their explosive offense to success this season, while the Reds are trying to climb back to .500 and remain relevant in the division race.

Quick Picks:
Best Bet: Reds +1.5 (-161) ★★★★☆
Top Prop: Nick Lodolo Over 5.5 Strikeouts (-120) ★★★☆☆
Value Play: Under 9 Runs (-111) ★★★★☆

Cubs vs Reds Betting Odds & Latest Line Movement

Market Cubs Reds
Moneyline -120 +100
Run Line -1.5 (+135) +1.5 (-161)
Total Over 9 (-109) Under 9 (-111)

Opening Line: Cubs -115, Total 9

Sharp Money Analysis: Where Pro Bettors Are Placing Their Wagers

The early movement on this game showed some sharp money coming in on the Cubs, pushing the line from -115 to -120. However, the action has stabilized, suggesting professionals aren’t convinced the Cubs deserve to be heavier favorites despite their offensive firepower. The total has remained steady at 9, which is interesting considering the Cubs’ recent scoring trends and Great American Ball Park’s reputation as a hitter-friendly venue.

Pitching Matchup: Ben Brown vs Nick Lodolo – Who Has the Edge?

Cubs: Ben Brown (3-3, 5.44 ERA)

  • 46.1 innings pitched with 58 strikeouts
  • Struggling with a high 1.55 WHIP
  • Allowing too many baserunners (16 BB)
  • Strikeout stuff is excellent (11.3 K/9)
  • Has been inconsistent throughout the season

Reds: Nick Lodolo (4-4, 3.22 ERA)

  • 58.2 innings pitched with 49 strikeouts
  • Impressive 1.06 WHIP shows excellent command
  • Limited walks (10 BB) demonstrates control
  • Left-hander who could neutralize Cubs’ lefty hitters
  • Coming off a quality start against the Braves

Advantage: Reds – Lodolo has been the more consistent pitcher and has better overall numbers. His low WHIP and ERA give Cincinnati a significant edge in the starting pitching matchup.

Bullpen Breakdown

The Cubs’ bullpen has been a mixed bag this season, recently designating struggling reliever Julian Merryweather for assignment and calling up Brooks Kriske. While they’ve had some success, consistency has been an issue. The Reds’ bullpen ranks 10th in MLB with a collective 3.68 ERA, giving them a slight advantage in late-inning situations. Both teams may need to utilize multiple relievers today, particularly if Brown struggles early for Chicago.

Key Betting Trends & Team Statistics That Matter

  • Cubs are 25-4 when scoring at least 5 runs this season
  • Reds are 14-13 at home, showing they’re competitive at Great American Ball Park
  • Cubs are 7-3 in their last 10 games, averaging 7.2 runs per game
  • Reds are 6-4 in their last 10 games with a 3.38 team ERA during that span
  • Cubs have gone OVER the total in 7 of their last 10 games
  • Reds have gone UNDER in 7 of their last 10 games with 1 push
  • Cubs are 16-11 on the road this season
  • Reds are 6-4 ATS in their last 10 games

Player Spotlight: Seiya Suzuki Heating Up

Seiya Suzuki enters this game on a five-game hitting streak, batting a scorching .429 with three doubles, two home runs, three walks, and seven RBIs during this stretch. He’s been a key contributor to the Cubs’ offensive success and has 46 RBIs on the season, tied for team lead. The Reds will need to be careful with him, especially in high-leverage situations.

Great American Ball Park Factor: How the Venue Influences Today’s Game

Great American Ball Park is notorious for being hitter-friendly, ranking consistently among the top ballparks for home runs. However, with Lodolo on the mound for Cincinnati, this advantage may be somewhat neutralized. The left-handed pitcher’s ability to keep the ball down and generate ground balls could be crucial in this environment. Weather conditions show moderate temperatures with light winds, which shouldn’t significantly impact ball flight today.

Expert Prediction & Best Bets for Cubs-Reds Showdown

Primary Play: Reds +1.5 (-161)

While the juice is a bit heavy here, this is still the smartest play on the board. Nick Lodolo has been significantly more consistent than Ben Brown this season, and the Reds have been competitive at home. Even if Cincinnati doesn’t win outright, they should keep this game close. The Cubs’ explosive offense is always a threat, but Lodolo’s strong command and ability to limit free passes should keep the Reds within striking distance.

Strong Value Play: Under 9 Runs (-111)

This might seem counterintuitive with the Cubs’ high-scoring tendencies and Great American Ball Park’s reputation, but there’s value on the Under today. Lodolo’s efficiency and ability to generate quick outs should limit Chicago’s opportunities. Additionally, the Reds have trended toward the Under lately (7-2-1 in their last 10), and Brown, despite his struggles, still has swing-and-miss stuff that can limit damage. Expecting something in the 4-3 or 5-3 range.

Worth Considering: Reds Moneyline (+100)

Getting the Reds at even money at home with their better starting pitcher on the mound represents solid value. Cincinnati has been playing improved baseball lately, and Lodolo gives them a legitimate chance to win this rubber match outright. The Cubs’ offense is dangerous, but if Lodolo can work efficiently through 6+ innings, the Reds should have a real shot at the series victory.

Player Props Worth Targeting in Today’s Matchup

Player Prop Odds Rating
Nick Lodolo Over 5.5 Strikeouts -120 ★★★★☆
Seiya Suzuki Total Bases Over 1.5 +100 ★★★☆☆
Elly De La Cruz To Record an RBI +145 ★★★★☆
Ben Brown Under 4.5 Innings Pitched -115 ★★★☆☆

Final Thoughts: Pitching Should Prevail in Division Rivalry

While the Cubs have been an offensive juggernaut lately, this matchup features a quality Reds starter in Lodolo who has the stuff to quiet their bats. I’m expecting a moderately lower-scoring affair than the market anticipates, with Cincinnati having a legitimate chance to take the series. Brown’s inconsistency and high WHIP are concerning against a Reds lineup that has shown improvement. The key factor will be whether Lodolo can work efficiently and hand a lead to the bullpen in the later innings.

Score Prediction: Reds 5, Cubs 3

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